Maganin Dengue NS1, IgM/IgG Mai Hana Kamuwa da Cututtuka Biyu

Zazzabin Dengue cuta ce mai saurin yaɗuwa wadda ke faruwa sakamakon cizon sauro mata masu ɗauke da ƙwayar cutar Dengue (DENV), tare da saurin yaɗuwa, yawan kamuwa da ita, yaɗuwa, da kuma mace-mace mai yawa a cikin mawuyacin hali.^.

Kimanin mutane miliyan 390 a duk duniya ke kamuwa da zazzabin dengue kowace shekara, inda mutane miliyan 96 ke kamuwa da cutar a cikin ƙasashe sama da 120, mafi muni a Afirka, Amurka, Kudu maso Gabashin Asiya da Yammacin Pacific. Yayin da ɗumamar yanayi ke ƙaruwa, zazzabin dengue yanzu yana yaɗuwa zuwa yankuna masu sanyi da sanyi da tsaunuka mafi girma, kuma yawan nau'ikan serotypes yana canzawa. A cikin 'yan shekarun nan, yanayin annobar cutar zazzabin dengue ya fi tsanani a yankin Kudancin Pacific, Afirka, Kudancin Amurka, Kudancin Asiya da Kudu maso Gabashin Asiya, kuma yana nuna matakai daban-daban na ƙaruwa a nau'in serotype da ke yaɗuwa, yankin tsayi, yanayi, yawan mace-mace da adadin kamuwa da cuta.

Bayanan hukuma na WHO a watan Agusta na 2019 sun nuna cewa akwai kimanin mutane 200,000 da suka kamu da cutar zazzabin dengue da kuma mutuwar mutane 958 a Philippines. Malaysia ta tara fiye da mutane 85,000 da suka kamu da cutar dengue a tsakiyar watan Agusta na 2019, yayin da Vietnam ta tara mutane 88,000. Idan aka kwatanta da wannan lokacin a shekarar 2018, adadin ya karu da ninki biyu a kasashen biyu. WHO ta dauki cutar zazzabin dengue a matsayin babbar matsalar lafiyar jama'a.

Wannan samfurin kayan aiki ne mai sauri, a wurin aiki kuma mai inganci don gano ƙwayoyin cuta na dengue NS1 antigen da IgM/IgG antibody. Takamaiman maganin rigakafi na IgM yana nuna cewa akwai kamuwa da cuta kwanan nan, amma gwajin IgM mara kyau ba ya tabbatar da cewa jiki ba shi da kamuwa da cuta. Haka kuma, ya zama dole a gano takamaiman ƙwayoyin rigakafi na IgG waɗanda ke da tsawon rabin rayuwa da mafi girman abun ciki don tabbatar da ganewar asali. Bugu da ƙari, bayan kamuwa da cuta, maganin rigakafi na NS1 ya fara bayyana, don haka gano ƙwayar cuta ta dengue NS1 antigen da takamaiman ƙwayoyin rigakafi na IgM da IgG na iya gano martanin garkuwar jiki ga takamaiman ƙwayoyin cuta, kuma wannan kayan aikin gano antigen-antibody mai haɗin gwiwa na iya yin bincike da sauri da wuri a matakin farko na kamuwa da cutar dengue, kamuwa da cuta ta farko da kamuwa da cutar dengue ta biyu ko ta da yawa, rage lokacin taga da inganta ƙimar ganowa.