Dengue NS1 Antigen, IgM/IgG Antibody Dual

Zazzabin Dengue cuta ce mai saurin kamuwa da cuta ta hanyar cizon sauro mata masu ɗauke da kwayar cutar dengue (DENV), tare da saurin yaɗuwa, yawan kamuwa da cuta, kamuwa da cuta mai yawa, da yawan mace-mace a lokuta masu tsanani.^.

Kimanin mutane miliyan 390 a duniya ke kamuwa da cutar zazzabin Dengue kowace shekara, inda mutane miliyan 96 ke kamuwa da cutar a cikin kasashe sama da 120, mafi muni a Afirka, Amurka, Kudu maso Gabashin Asiya da Yammacin Pacific. Yayin da dumamar yanayi ke ƙaruwa, zazzabin dengue a yanzu yana yaduwa zuwa yankuna masu sanyi da sanyi da kuma tudu masu tsayi, kuma yawan ƙwayoyin serotypes na canzawa. A cikin 'yan shekarun nan, yanayin cutar zazzabin dengue ya fi tsanani a yankin Kudancin Pacific, Afirka, Amurka ta Kudu, Kudancin Asiya da kudu maso gabashin Asiya, kuma yana nuna nau'in nau'in watsawa na serotype, yanayin tsayi, yanayi, yawan mace-mace da adadin cututtuka.

Alkaluman hukumar ta WHO a watan Agustan 2019 sun nuna cewa akwai kimanin mutane 200,000 na zazzabin dengue da kuma mutuwar mutane 958 a Philippines. Malesiya ta tara sama da cutar dengue sama da 85,000 a tsakiyar watan Agusta 2019, yayin da Vietnam ta tara shari'o'i 88,000. Idan aka kwatanta da lokaci guda a cikin 2018, adadin ya ƙaru fiye da ninki biyu a cikin ƙasashen biyu. WHO ta dauki zazzabin dengue a matsayin babbar matsalar lafiyar jama'a.

Wannan samfuri ne mai sauri, kan-site kuma ingantaccen kayan ganowa don ƙwayar dengue NS1 antigen da IgM/IgG antibody. Specific IgM antibody yana nuna cewa akwai kamuwa da cuta kwanan nan, amma gwajin IgM mara kyau baya tabbatar da cewa jikin bai kamu da cutar ba. Hakanan wajibi ne a gano takamaiman ƙwayoyin rigakafi na IgG tare da tsawon rabin rayuwa da mafi girman abun ciki don tabbatar da ganewar asali. Bugu da kari, bayan da jiki ya kamu da cutar, da NS1 antigen bayyana farko, don haka da lokaci guda gano da dengue cutar NS1 antigen da takamaiman IgM da IgG antibodies iya yadda ya kamata bincikar jikin ta rigakafi da martani ga wani takamaiman pathogen, da kuma wannan antigen-antibody hada ganewa kit iya yi da sauri farkon ganewar asali da kuma nunawa a cikin farkon mataki na dengue kamuwa da cuta, na farko da kamuwa da cuta da kuma na biyu lokaci.