Kowace shekara a ranar 17 ga Afrilu ita ce Ranar Ciwon Daji ta Duniya.
01 Bayani Kan Abin da Ya Faru a Duniya Kan Cutar Daji
A cikin 'yan shekarun nan, tare da ci gaba da ƙaruwar rayuwar mutane da matsin lamba na kwakwalwa, yawan kamuwa da ciwon daji yana ƙaruwa kowace shekara.
Ciwon daji mai tsanani (ciwon daji) ya zama ɗaya daga cikin manyan matsalolin lafiyar jama'a da ke barazana ga lafiyar al'ummar China. A cewar sabbin bayanan kididdiga, mutuwar ciwon daji mai tsanani ya kai kashi 23.91% na dukkan abubuwan da ke haifar da mace-mace a tsakanin mazauna, kuma yawan mace-macen da kuma mutuwar ciwon daji mai tsanani ya ci gaba da ƙaruwa a cikin shekaru goma da suka gabata. Amma ciwon daji ba yana nufin "hukuncin kisa ba." Hukumar Lafiya ta Duniya ta nuna a fili cewa muddin aka gano shi da wuri, kashi 60%-90% na ciwon daji za a iya warkar da su! Kashi ɗaya bisa uku na ciwon daji ana iya hana su, kashi ɗaya bisa uku na ciwon daji ana iya warkar da su, kuma kashi ɗaya bisa uku na ciwon daji za a iya magance su don tsawaita rayuwa.
02 Menene ciwon daji
Ciwon daji yana nufin sabuwar halitta da aka samar ta hanyar yaduwar ƙwayoyin nama na gida a ƙarƙashin tasirin abubuwa daban-daban na ciwon daji. Bincike ya gano cewa ƙwayoyin ciwon daji suna fuskantar canje-canje na rayuwa daban-daban daga ƙwayoyin halitta na yau da kullun. A lokaci guda, ƙwayoyin ciwon daji na iya daidaitawa da canje-canje a cikin yanayin rayuwa ta hanyar canzawa tsakanin glycolysis da oxidative phosphorylation.
03 Maganin Ciwon Daji na Musamman
Maganin ciwon daji na mutum ɗaya ya dogara ne akan bayanan ganewar asali na kwayoyin halittar da aka yi niyya ga cututtuka da kuma sakamakon binciken likita bisa shaida. Yana ba da tushe ga marasa lafiya don karɓar tsarin magani daidai, wanda ya zama yanayin ci gaban likitanci na zamani. Nazarin asibiti ya tabbatar da cewa ta hanyar gano maye gurbin kwayoyin halitta na biomarkers, nau'in kwayar halitta ta SNP, kwayar halitta da matsayin bayyanar furotin a cikin samfuran halittu na marasa lafiya da ciwon daji don annabta ingancin magani da kimanta hasashen, da kuma jagorantar maganin asibiti na mutum ɗaya, yana iya inganta inganci da rage halayen da ba su dace ba, don haɓaka amfani da albarkatun likita da kyau.
Za a iya raba gwajin ƙwayoyin cuta na ciwon daji zuwa manyan nau'i uku: ganewar asali, gado, da kuma magani. Gwajin magani shine ginshiƙin abin da ake kira "cututtukan magani" ko magani na musamman, kuma ana iya amfani da ƙarin ƙwayoyin rigakafi da ƙananan ƙwayoyin cuta waɗanda za su iya kai hari ga mahimman kwayoyin halitta da hanyoyin sigina na musamman ga ciwon daji don maganin ciwon daji.
Maganin ciwon daji da aka yi niyya ga ƙwayoyin halitta yana kai hari ga ƙwayoyin halittar ciwon daji kuma yana shiga cikin tsarin ƙwayoyin cutar kansa. Tasirinsa galibi yana kan ƙwayoyin ciwon daji ne, amma ba shi da tasiri sosai ga ƙwayoyin halitta na yau da kullun. Masu karɓar abubuwan da ke haifar da ci gaban ciwon daji, ƙwayoyin halittar da ke canza siginar, sunadaran zagayowar ƙwayoyin halitta, masu daidaita apoptosis, enzymes na proteolytic, abubuwan da ke haifar da ci gaban jijiyoyin jini, da sauransu duk ana iya amfani da su azaman abubuwan da ke haifar da ci gaban ciwon daji. A ranar 28 ga Disamba, 2020, "Matakan Gudanarwa don Amfani da Magungunan Antineoplastic na Asibiti (Gwaji)" wanda Hukumar Lafiya da Lafiya ta Ƙasa ta fitar ya nuna a sarari cewa: Ga magunguna masu ɗauke da takamaiman abubuwan da ke haifar da ci gaban ƙwayar cuta, dole ne a bi ƙa'idar amfani da su bayan gwajin kwayar halitta da aka yi niyya.
04 Gwajin kwayoyin halitta da aka yi niyya ga ciwon daji
Akwai nau'ikan maye gurbi na kwayoyin halitta da yawa a cikin ciwace-ciwacen daji, kuma nau'ikan maye gurbi na kwayoyin halitta daban-daban suna amfani da magunguna daban-daban da aka yi niyya. Sai dai ta hanyar fayyace nau'in maye gurbi na kwayoyin halitta da kuma zaɓar maganin da aka yi niyya daidai ne marasa lafiya za su iya amfana. An yi amfani da hanyoyin gano kwayoyin halitta don gano bambancin kwayoyin halitta da ke da alaƙa da magungunan da aka saba niyya a cikin ciwace-ciwacen. Ta hanyar nazarin tasirin bambance-bambancen kwayoyin halitta akan ingancin magani, za mu iya taimaka wa likitoci su ƙirƙiri tsarin magani mafi dacewa.
05 Magani
Macro & Micro-Test sun ƙirƙiro jerin kayan gano ƙwayoyin cuta don gano ƙwayoyin cuta, suna samar da mafita gabaɗaya don maganin da aka yi niyya ga ƙwayoyin cuta.
Kayan Gano Canje-canje na Halittar Dan Adam EGFR 29 (PCR mai haske)
Ana amfani da wannan kayan aiki don gano sauye-sauyen da aka saba samu a cikin kwayar halittar EGFR ta hanyar gwaji a cikin fitsari a cikin samfuran da aka samo daga marasa lafiya da ke fama da cutar kansar huhu ta ɗan adam waɗanda ba ƙananan ƙwayoyin halitta ba.
1. Tsarin yana gabatar da tsarin kula da ingancin bincike na ciki, wanda zai iya sa ido sosai kan tsarin gwaji da kuma tabbatar da ingancin gwajin.
2. Babban ƙarfin ji: Gano maganin amsawar nucleic acid zai iya gano ƙimar maye gurbi na 1% a ƙarƙashin asalin nau'in daji na 3ng/μL.
3. Babban takamaiman bayani: Babu haɗin kai tsakanin kwayoyin halittar ɗan adam na nau'in daji da sauran nau'ikan maye gurbi.
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Kayan Gano Canje-canje na KRAS 8 (PCR mai haske)
An yi nufin wannan kayan aikin don gano maye gurbi guda 8 a cikin kwayar halittar K-ras ta codons 12 da 13 a cikin DNA da aka cire daga sassan cututtukan da aka haɗa da paraffin na ɗan adam.
1. Tsarin yana gabatar da tsarin kula da ingancin bincike na ciki, wanda zai iya sa ido sosai kan tsarin gwaji da kuma tabbatar da ingancin gwajin.
2. Babban ƙarfin ji: Gano maganin amsawar nucleic acid zai iya gano ƙimar maye gurbi na 1% a ƙarƙashin asalin nau'in daji na 3ng/μL.
3. Babban takamaiman bayani: Babu haɗin kai tsakanin kwayoyin halittar ɗan adam na nau'in daji da sauran nau'ikan maye gurbi.
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Kayan Gano Canjin Halittar Haɗakar Halittar Dan Adam na EML4-ALK (Fluorescence PCR)
Ana amfani da wannan kayan aiki don gano nau'ikan maye gurbi guda 12 na kwayar halittar haɗin EML4-ALK a cikin samfuran marasa lafiya da ke fama da cutar kansar huhu ta ɗan adam a cikin vitro.
1. Tsarin yana gabatar da tsarin kula da ingancin bincike na ciki, wanda zai iya sa ido sosai kan tsarin gwaji da kuma tabbatar da ingancin gwajin.
2. Babban ƙarfin ji: Wannan kayan aikin zai iya gano maye gurbi mai kama da juna har zuwa kwafi 20.
3. Babban takamaiman bayani: Babu haɗin kai tsakanin kwayoyin halittar ɗan adam na nau'in daji da sauran nau'ikan maye gurbi.
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Kayan Gano Canjin Halittar ROS1 na Dan Adam (Fluorescence PCR)
Ana amfani da wannan kayan aiki don gano nau'ikan maye gurbi guda 14 na ROS1 a cikin samfuran cutar kansar huhu na ɗan adam waɗanda ba ƙananan ƙwayoyin halitta ba.
1. Tsarin yana gabatar da tsarin kula da ingancin bincike na ciki, wanda zai iya sa ido sosai kan tsarin gwaji da kuma tabbatar da ingancin gwajin.
2. Babban ƙarfin ji: Wannan kayan aikin zai iya gano maye gurbi mai kama da juna har zuwa kwafi 20.
3. Babban takamaiman bayani: Babu haɗin kai tsakanin kwayoyin halittar ɗan adam na nau'in daji da sauran nau'ikan maye gurbi.
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Kayan Gano Canjin Halittar Dan Adam na BRAF V600E (Fluorescence PCR)
Ana amfani da wannan kayan gwajin don gano maye gurbin kwayar halittar BRAF V600E a cikin samfuran kyallen da aka haɗa da paraffin na melanoma na ɗan adam, ciwon daji na hanji, ciwon thyroid da ciwon huhu a cikin vitro.
1. Tsarin yana gabatar da tsarin kula da ingancin bincike na ciki, wanda zai iya sa ido sosai kan tsarin gwaji da kuma tabbatar da ingancin gwajin.
2. Babban ƙarfin ji: Gano maganin amsawar nucleic acid zai iya gano ƙimar maye gurbi na 1% a ƙarƙashin asalin nau'in daji na 3ng/μL.
3. Babban takamaiman bayani: Babu haɗin kai tsakanin kwayoyin halittar ɗan adam na nau'in daji da sauran nau'ikan maye gurbi.
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| Lambar Kasida | Sunan Samfuri | Ƙayyadewa |
| HWTS-TM012A/B | Kayan Gano Canje-canje na Halittar Dan Adam EGFR 29 (Fluorescence PCR) | Gwaje-gwaje 16/kit, gwaje-gwaje 32/kit |
| HWTS-TM014A/B | Kayan Gano Canje-canje na KRAS 8 (PCR mai haske) | Gwaje-gwaje 24/kit, gwaje-gwaje 48/kit |
| HWTS-TM006A/B | Kayan Gano Canjin Halittar Haɗakar Jini na Ɗan Adam na EML4-ALK (Fluorescence PCR) | Gwaje-gwaje 20/kit, gwaje-gwaje 50/kit |
| HWTS-TM009A/B | Kayan Gano Canjin Halittar ROS1 na Dan Adam (Fluorescence PCR) | Gwaje-gwaje 20/kit, gwaje-gwaje 50/kit |
| HWTS-TM007A/B | Kayan Gano Canjin Halittar Dan Adam na BRAF V600E (Fluorescence PCR) | Gwaje-gwaje 24/kit, gwaje-gwaje 48/kit |
| HWTS-GE010A | Kayan Gano Canjin Halittar Haɗakar BCR-ABL na Ɗan Adam (Fluorescence PCR) | Gwaje-gwaje 24/kayan aiki |
Lokacin Saƙo: Afrilu-17-2023