Samfurin da aka sarrafa shi gaba ɗaya zuwa ga amsa C. Gano Cututtukan da suka Shafi Bambanci

Me ke haifar da kamuwa da cutar C. Diff?

C. Ana kamuwa da cutar Diff ta hanyar kwayar cuta da aka sani daClostridioides difficile (C. difficile), wanda yawanci yana zaune a cikin hanji ba tare da lahani ba. Duk da haka, idan aka sami matsala a cikin daidaiton ƙwayoyin cuta na hanji, wanda galibi ana amfani da shi azaman maganin rigakafi mai faɗi, C. difficile na iya girma da yawa kuma ya haifar da guba, wanda ke haifar da kamuwa da cuta.

Wannan kwayar cuta tana wanzu a cikin duka biyunmai gubada kuma nau'ikan da ba sa haifar da guba, amma nau'ikan guba kawai (guba A da B) suna haifar da cututtuka. Suna haifar da kumburi ta hanyar lalata ƙwayoyin epithelial na hanji. Guba A galibi enterotoxin ne wanda ke lalata layin hanji, yana ƙara yawan aiki, kuma yana jawo ƙwayoyin rigakafi waɗanda ke fitar da cytokines masu kumburi. Guba B, wani sinadari mai ƙarfi na cytotoxin, yana kai hari ga cytoskeleton na ƙwayoyin halitta, yana haifar da zagayen ƙwayoyin halitta, rabuwa, da kuma mutuwar ƙwayoyin halitta. Tare, waɗannan gubobi suna haifar da lalacewar nama da kuma amsawar garkuwar jiki mai ƙarfi, wanda ke bayyana a matsayin colitis, gudawa, kuma a cikin mawuyacin hali, pseudomembranous colitis - kumburi mai tsanani na hanji.

Ta yayaC. Bambanciyaɗa?

C. Diff yana yaduwa cikin sauƙi. Yana nan a asibitoci, galibi ana samunsa a cikin asibitocin kwantar da hankali (ICUs), a hannun ma'aikatan asibiti, a kan benaye da sandunan hannu na asibiti, a kan na'urorin auna zafin jiki na lantarki, da sauran kayan aikin likita...

Abubuwan da ke Haɗarin Kamuwa da Cutar C. Bambanci

• ●Asibiti na dogon lokaci;

• ●Maganin ƙwayoyin cuta;

• ●Ma'aikatan maganin chemotherapy;

• ●Tiyatar da aka yi kwanan nan (hannun riga na ciki, hanyar shiga ciki, tiyatar hanji);

• ●Abinci mai gina jiki na Naso-gastric;

• ●Kamuwa da cuta ta C. diff ta farko;

Alamomin kamuwa da cutar C. Diff

C. kamuwa da cuta mai kama da cuta na iya zama da matuƙar rashin jin daɗi. Yawancin mutane suna fama da gudawa da rashin jin daɗi a cikin ciki. Alamomin da suka fi yawa sune: gudawa, ciwon ciki, tashin zuciya, rashin ci, zazzaɓi.

Yayin da kamuwa da cutar C. diff ke ƙara tsanani, za a sami ci gaban wani nau'in C. diff mai rikitarwa wanda aka sani da colitis, pseudomembranous enteritis har ma da mutuwa.

Ganewar Ganewana C. Yaduwa Kamuwa da cuta

Al'adun Bakteriya:Mai saurin kamuwa amma yana ɗaukar lokaci (kwana 2-5), ba zai iya bambance nau'ikan guba da waɗanda ba sa haifar da guba ba;

Al'adun Guba:yana gano nau'ikan guba waɗanda ke haifar da cututtuka amma suna ɗaukar lokaci (kwanaki 3-5) kuma ba su da saurin kamuwa da cuta;

Gano GDH:sauri (awanni 1-2) kuma mai inganci, mai saurin kamuwa da cuta amma ba zai iya bambance nau'ikan guba da marasa guba ba;

Gwajin Tsarkakewar Tsarkakewar Kwayoyin Halitta (CCNA):yana gano gubar A da B tare da yawan jin zafi amma yana ɗaukar lokaci (kwana 2-3), kuma yana buƙatar kayan aiki na musamman da ma'aikata masu horo;

Toxin A/B ELISAGwaji mai sauƙi da sauri (awa 1-2) tare da ƙarancin ji da kuma yawan kuskuren da aka saba gani;

Gwaje-gwajen Ƙarfafa Acid na Nucleic (NAATs): Yana da sauri (awa 1-3) kuma yana da matuƙar saurin kamuwa da cuta, yana gano kwayoyin halittar da ke haifar da guba;

Bugu da ƙari, ana iya amfani da gwaje-gwajen hoto don duba hanji, kamar CT scans da X-rays, don taimakawa wajen gano cutar C. diff da kuma rikitarwa na C. diff, kamar colitis.

Maganin kamuwa da cutar C. Diff

Akwai zaɓuɓɓukan magani da yawa donC. kamuwa da cuta mai tsananiGa mafi kyawun zaɓuɓɓuka:

• ●Ana amfani da magungunan rigakafi na baki kamar vancomycin, metronidazole ko fidaxomicin domin maganin zai iya ratsawa ta cikin tsarin narkewar abinci ya isa babban hanji inda ƙwayoyin cuta na C. diff ke zaune.

• ●Ana iya amfani da metronidazole da aka yi amfani da shi a cikin jijiya don magani idan kamuwa da cutar C. diff ya yi tsanani.

• ●Dashen ƙwayoyin cuta na najasa ya nuna inganci wajen magance cututtukan C. diff akai-akai da kuma cututtukan C. diff masu tsanani waɗanda ba sa amsawa ga maganin rigakafi.

• ●Tiyata na iya zama dole ga masu fama da matsaloli masu tsanani.

Maganin ganewar asali daga MMT

Domin neman hanzarta gano C. difficile daidai, mun gabatar da sabuwar Kayan Gano Nucleic Acid don kwayar halittar Clostridium difficile toxin A/B, wanda ke ƙarfafa ƙwararrun ma'aikatan kiwon lafiya su yi bincike da wuri da kuma daidai da kuma tallafawa yaƙi da kamuwa da cututtukan da ake kamuwa da su a asibiti.

图片链接：

• 
  
  ●Babban Jin Daɗi: Yana gano ƙasa kamar200 CFU/mL,;

• 
  
  ●Daidaitaccen Manufofi: Yana gano kwayar halittar A/B mai guba ta C. mai wahala daidai, yana rage tasirin ƙarya;

• 
  
  ●Gano Cututtuka Kai Tsaye: Yana amfani da gwajin nucleic acid don gano kwayoyin halittar guba kai tsaye, yana kafa ma'aunin zinare don gano cututtuka.

• 
  
  ●Cikakken jituwa damanyan kayan aikin PCR suna magance ƙarin dakunan gwaje-gwaje;

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