Drbreaking Tb da mafita na maganin bincike ta #Macro & scor -Test!

Wani sabon makami na cutar tarin fuka da gano ƙwayar magani: Sabuwar ƙarar da aka yi da aka yi wa jabu

Rahoton wallafe-wallafen: CCA: Model na bincike dangane da TNGs da kuma koyon injin, wanda ya dace da mutane rashin cututtukan ƙwayar cuta da cututtukan ƙwayar cuta.

Takaddanci na Taken: An yi niyya mai girman kai na gaba da injiniya: Tsarin Koyon Injin-mai mahimmanci: Tsarin Bincike na Pacmonyarina Tubular Tubulary.

Lokaci: "Clindica Chimica Acta"

Idan: 6.5

Ranar Bayarwa: Janairu 2024

A haɗe tare da Jami'ar Kwalejin Kimiyya ta Kimiyya ta Kimiyya ta Kimiyya ta Cibiyar Likita ta Beijing ta birnin kasar Leijing Tsammani da cutar tarin fuka tare da ƙwayoyin cuta da ƙwayoyin cuta, sun ba da sabon hanyar gano cutar hyperensitosis don gano cutar asibiti iri ɗaya tarin fuka, kuma ya taimaka wa ingantaccen ganewar asali, gano juriya da magani da magani na tarin fuka. A lokaci guda, ana gano cewa plasma plasma za a iya amfani dashi azaman nau'in samfurin da ya dace don samfuri mai dacewa a cikin kamuwa da cutar tbm.

A cikin wannan binciken, an yi amfani da samfurori 22 na PASSMA da samfuran ruwa na asibiti, wanda ake amfani da samfuran ƙwayoyin cuta na cutar tarin fuka, kuma a cikin masanin ilimin cututtukan cututtukan cututtukan cuta don tabbatar da kafa. samfurin bincike. Duk samfurori sun fara yin niyya ta musamman da aka tsara musamman da aka yi niyya don kama pool pool don pool na Mycebacerium. Bayan haka, dangane da bayanan da aka yanke na TB-TNGs din, ana yin samfurin ƙirar don yin ingancin tsarin binciken abubuwa 5 a kan horon binciken plasma da samfuran bincike na plasma da samfuran ruwa da aka samu. Eleveran ƙofar da aka samu an kawo shi zuwa tsarin gwajin asibiti guda biyu na gano asali na asibiti don ganowa, kuma aikin bincike na koyawa yana kimanta ta hanyar roc kwana. A ƙarshe, an samo samfurin cutar ƙwayar cutar ƙwayar cuta.

Fig. 1 Tsarin zane na Design Bincike

Sakamako: gwargwadon takamaiman ƙafar CSF DNA samfurin (Auction) da Plasma CFDNA Samfura (AUC = 0.908), da kuma takamaiman samfurin shine 95.65%, kuma Abin sani da ingancin samfurin plasma sun kasance 82.61% da 86.36%. A cikin nazarin samfurori 44 na Plasma CFNNA da CiberBrospinal ruwa na tbm, dabarun wannan binciken yana da babban aiki na 90.94) a Plasma CFKNA da DNA MEARPORSPININININE (40/44) (42/44). In children with pulmonary tuberculosis, the diagnostic strategy of this study is more sensitive to plasma samples than the Xpert detection results of gastric juice samples from the same patients (28.57% VS 15.38%).

Fig

Hoto na 3 na asali na samfurori

Kammalawa: Hanya mai hypermenter ga tarin fuka da aka kafa ta tarin fuka a cikin wannan binciken, wanda zai iya samar da kayan aikin bincike tare da marasa jinin asibiti tare da cututtukan cututtukan asibiti (al'adun mara kyau). Gano na cutar cutar cututtukan cutar tarin fuka da aka danganta da plasma Cffle na iya zama nau'in bayyanar cututtuka da tarin plebrospines da ake zargi da cutar kwakwalwa).

Hanyar asali: https://www.Ski.Ssictionsdict.com/Siyya/Atardi/pii/s000989812300490? ta hanyar% 3dihub

Takaitaccen gabatarwar Macro & Micro-gwajin tarin kayayyakin ganowa

Ganin yanayin yanayin mai rikitarwa na marassa lafiyar tarin fuka da kuma buƙatun macro & microd-gwajin yana samar da cikakken tsarin tsirarun NGS na hakar Sputum da Sihiri da Sihiri. Abubuwan da ke cike da saurin kamuwa da cutar tarin fuka, gano jingina cututtukan ƙwayar cuta da ntm, cututtukan fata, cututtukan ƙwayar cuta, da sauransu.

Sial gano abubuwan tarin fuka da mycebacteria:

Abu babu Sunan Samfuta abun cikin gwajin samfurin Samfurin samfurin samfurin da aka zartar
Hwts-3012 Wakilin Saki Saki Amfani da shi a cikin maganin maye na sputum samfurori, ya sami lambar rikodin ta farko, kayan aikin suttura 2020047. sputum
Hwts-ngs-p00021 Ka'idojin gano kit ɗin na Tattaunawa don tungun cutar cututtukan cututtukan fata (hanyar kama da) Ganowar da ba mai fama da ruwa ba (ganowa ruwa) gano ƙwayar cuta game da cututtukan ƙwayar cuta mara kyau da tarin fuka na ƙwayar cuta da ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa; Samfuran da ake zargi da ake zargi da cutar da cutar tarin fuka ko kuma gano bayanan jingina na farko na magungunan mycebacterium An bayar da su. Jinin jini, alvolar sanye da ruwa, hydrothorax da ascites, samfurin punctcctor, ruwa sabo. Tsara na biyu
Hwts-ngs-t001 Rubutun Myceberiterium Gwajin Mycebiterium, gami da MTBC da 187 ntm;Ganowar juriya na Mycebacterium Magunguna tarin fuka 13 ya rufe magunguna 13 da kuma manyan kayan maye gurbi na magunguna. Sputum, alverolar sanye da ruwa, hydrothorax da ascites, samfurin punctcctor, ruwa sabo. Na biyu / na uku tsara squirent

Babban karin bayani: HWS-ngs-ngs-Trapperium dencing jinginan discomenctionsan magani (hanyar amplification hanya)

Gabatarwar Samfurin

Magungunan sun dogara da manyan magungunan farko da na farko da aka bayyana a cikin jagororin magani na yau da kullun a cikin wuraren kula da magunguna na NTM. Wanene Mycobcacteros Commuctionosis Castings Patput, da sauran rahoton magunguna kwayoyin halittun kwayoyin halitta bisa ga binciken da ƙididdigar babban bincike Littattafai a gida da kasashen waje.

Rubutun Rubzu yana da asali akan nau'ikan NTM Tattaunawa a cikin jagororin NTM wanda aka buga a Jagorar NTMBuka da cututtukan numfashi da cututtukan na numfashi da kuma rikice-rikice. Tsarin ambulan da aka tsara na iya fadada, jerin da kuma an soke fiye da shekarun Ntm sama da 190.

Ta hanyar da aka yi niyya ga fasaha ta Micr, kayan kwayoyin halittar da kwayoyi na mycebacterium sun fito da aka gano an gano an gano an gano aka samu. Za'a iya gina samfuran amplified zuwa ɗakunan karatu na zamani ko na zamani, kuma duk dandamali na zamani da na biyu za a iya tilasta su da jerin abubuwan zurfafa-zuriyar halittu. Ta hanyar gwada tare da sanannen maye gurbi da ke cikin ginannun bayanan da aka gindaya (ciki har da wanda cutar ƙwayar cuta), maye gurbi na magunguna tarin fiyya. Haɗe tare da buɗe samfurin sputum da kansa na maganin macro & micro-gwajin, matsalar ƙarancin ƙwayar ƙwayar cuta) kai tsaye amfani da samfuran sputum na asibiti.

Kewayon gano samfurin

34Magungunan juriya da kwayoyin halitta na18magungunan maganin cututtukan dabbobi da6An gano magunguna na NTM, sutura297shafukan juriya; Nau'ikan goma sha-kercoebcoosis da fiye da190An gano nau'ikan Ntm.

Tebur 1: Bayanai na 18 + 6 kwayoyi + 190 + ntm

Amfani da kaya

Mai ƙarfi na daidaitawa: Za a iya gano samfurori na sputum tare da wakilin kafada ba tare da al'adu ba.

Aikin gwaji ne mai sauki: zagaye na farko na ampliation yana da sauki, kuma an kammala ginin ɗakin karatu a cikin awanni 3, wanda ya inganta ingancin aikin.

M daukakancin magunguna: Murayya da wuraren bugun tarko, da wuraren juriyar magunguna na MTB da NTM, su ne ke tallafa wa Software na Binciken Murfurori, da samar da rahoton bincike na bincike tare da danna daya.

Ka'ida: Karɓar Samfuri, daidaita zuwa Mainstream Ilm da MGI / ONT.

Musamman samfurin

Lambar samfurin Sunan Samfuta Gano dandikali muhawara
Hwts-ngs-t001 Mycebickerium Ont, illumina, mgi, salus pro 16 / 96RXN

Lokaci: Jana-23-2024