Bita naTakardar Bincike ta Classic
Kwayar cuta ta syncytial na numfashi (RSV) da Metapneumovirus (HMPV) sune two kusa da alaka pathogens a cikinPneumoviridaeiyaliwanda akai-akai rikicewa a lokuta na cututtukan cututtuka na numfashi na yara. Yayin da gabatarwar su ta asibiti ta zo kan gaba, bayanan sa ido na gaba (2016-2020) daga asibitocin yara na Amurka guda 7—wanda ya haɗa da marasa lafiya 8,605—sun bayyana bambance-bambance masu mahimmanci a cikin yawan haɗarinsu, tsananin cututtuka, da kulawar asibiti. Wannan binciken ya yi amfani da ƙira mai aiki, mai yiwuwa tare da tsarin nasopharyngeal swab tattarawa da gwaji don ƙwayoyin cuta na numfashi guda 8, yana ba da babban adadi na farko, kwatankwacin ainihin duniya ga likitocin yara. Ta hanyar nazarin ƙimar asibiti, shigar da ICU, amfani da iskar iska, da kuma tsawan lokaci na asibiti (≥3 kwanaki), yana kafa muhimmin tushe na rigakafin cutar kafin lokacin sabbin rigakafi na RSV (misali, rigakafi na uwa, ƙwayoyin rigakafi na monoclonal na dogon lokaci) da ƙirƙirar tsarin ci gaban rigakafin HMP na gaba.
Gano Maɓalli na 1: Filayen Mahimman Bayanan Haɗari
-RSV da farko yana shafar ƙananan jarirai:Tsakanin shekarun asibiti na watanni 7 ne kawai, tare da 29.2% na marasa lafiya da aka yarda da su ne ƙananan (0-2 months). RSV shine babban dalilin asibiti a jarirai a ƙasa da watanni 6, tare da tsananin da ya bambanta da shekaru.
-HMPV na kai hari ga manyan yara da waɗanda ke da cututtuka:Matsakaicin shekarun asibiti shine watanni 16, tare da babban tasiri akan yara fiye da shekara 1. Musamman, yaɗuwar yanayin rashin lafiya (misali, cututtukan zuciya, jijiya, numfashi) ya ninka fiye da sau biyu a cikin marasa lafiya na HMPV (26%) idan aka kwatanta da marasa lafiya na RSV (11%), yana nuna haɓakar raunin su.
Hoto 1. Rarraba shekarun shekarun ED da kuma asibitihade da RSV ko HMPV
a cikin yara 'yan kasa da shekaru 18.
Mabuɗin Neman 2: Bambance-banbance Gabatarwa na Clinical
-RSV yana bayyana tare da fitattun alamun numfashi na ƙasa:Yana da alaƙa mai ƙarfi tare da bronchiolitis (76.7% na lokuta na asibiti). Mabuɗin alamomi sun haɗa dakoma bayan bangon kirji (76.9% marasa lafiya; 27.5% ED)kumatachypnea (91.8% marasa lafiya; 69.8% ED), duka biyun suna da mahimmanci fiye da na HMPV.
-HMPV yana gabatar da babban zazzabi da haɗarin ciwon huhu:An gano ciwon huhu a cikin 35.6% na marasa lafiya na HMPV na asibiti - ninka adadin RSV.Zazzabi ya kasance mafi girman fasalin (83.6% marasa lafiya; 81% ED). Yayin da bayyanar cututtuka na numfashi kamar numfashi da tachypnea suna faruwa, gaba ɗaya ba su da tsanani fiye da RSV.
Hoto 2.Halayen kwatanta da na asibitihanyana RSV vs. HMPV a cikin yara a ƙarƙashin 18.
Taƙaice: RSVMafi yawa yana haifar da cututtuka mai tsanani a cikin ƙananan jarirai, wanda ke da alamun damuwa mai mahimmanci na numfashi (ƙumburi, retractions) da kuma bronchiolitis.HMPVya fi shafar manyan yara masu kamuwa da cuta, suna gabatar da zazzaɓi bayyananne, yana ɗauke da haɗarin ciwon huhu, kuma sau da yawa yana haifar da amsa mai kumburi mai faɗi.
Mabuɗin Neman 3: Mahimman Matsalolin Lokaci
-RSV yana da farkon, kololuwar tsinkaya:Ayyukansa sun fi mayar da hankali sosai, yawanci suna kololuwa tsakaninNuwamba da Janairu, yana mai da shi farkon barazanar kamuwa da cuta ga jarirai a cikin kaka da hunturu.
-HMPV yana girma daga baya tare da babban canji:Lokacin sa yana zuwa daga baya, yawanci yana shigaMaris da Afrilu, kuma yana nuna mahimmancin shekara zuwa shekara da bambancin yanki, sau da yawa yana bayyana a matsayin "taguwar ruwa na biyu" bayan RSV ya ƙi.
Hoto 3.Gabaɗaya kuma takamaiman wurin PCR positiveƙimar RSV da HMPV tsakanin yara 'yan ƙasa da 18 tare da kamuwa da cututtukan numfashi (ARI) masu alaƙa da ziyartar ED da asibiti.
Rigakafi da Kulawa: Tsare-tsaren Ayyuka na tushen Shaida
-RSV Prophylaxis:Akwai dabarun rigakafin yanzu. A cikin 2023, FDA ta Amurka ta amince da wani maganin rigakafi na monoclonal (Nirseimab), wanda zai iya kare jarirai tsawon watanni 5 na farko. Bugu da ƙari, allurar rigakafin RSV na uwa yadda ya kamata yana canza ƙwayoyin rigakafi ga jarirai.
-HMPV Prophylaxis:A halin yanzu babu magungunan rigakafin da aka yarda da su. Koyaya, 'yan takarar rigakafi da yawa (misali, AstraZeneca's RSV/HMPV hadewar rigakafin) suna cikin gwaji na asibiti. An shawarci iyaye da su kasance da masaniya game da sabbin abubuwa daga hukumomin kiwon lafiyar jama'a.
Nemi Hankalin Likitan Gaggawa ga KOWANE Daga Cikin "Jaran Tutoci":
-Zazzabi a cikin Jarirai:Zazzabi ≥38°C (100.4°F) a cikin kowane jariri a ƙasa da watanni 3.
-Maɗaukakin Ƙimar Numfashi:Numfashin ya wuce numfashi 60 a minti daya ga jarirai watanni 1-5, ko numfashi 40 a minti daya ga yara masu shekaru 1-5, wanda ke nuni da yuwuwar wahalar numfashi.
-Ƙananan Cike Oxygen:Oxygen saturation (SpO₂) ya faɗi ƙasa da 90%, alamar rashin lafiya mai tsanani da aka lura a cikin 30% na RSV da 32.1% na lokuta na asibiti na HMPV a cikin binciken.
-Matsalolin Ciyarwa ko Ƙarfafawa:Sanannen rashin jin daɗi ko raguwar shan madara da fiye da kashi ɗaya cikin uku a cikin sa'o'i 24, wanda zai iya zama mafarin rashin ruwa.
Duk da yake banbanta a cikin cututtukan cututtuka da gabatarwar asibiti, bambanta daidai tsakanin RSV da HMPV a wurin kulawa ya kasance mai ƙalubale. Bugu da ƙari, barazanar asibiti ta wuce waɗannan ƙwayoyin cuta guda biyu, tare da ƙwayoyin cuta kamar mura A da wasu nau'ikan ƙwayoyin cuta na ƙwayoyin cuta da ƙwayoyin cuta waɗanda ke barazana ga lafiyar jama'a a lokaci guda. Don haka daidai lokacin da daidaitaccen ganewar asali na etiological yana da mahimmanci don kulawa da tallafi da ya dace, keɓe mai inganci, da rabon albarkatu masu ma'ana.
Gabatar da AIO800 + 14-Pathogen Combined Detection Kit (Fluorescence PCR)(NMPA, CE, FDA, SFDA yarda)
Domin biyan wannan bukata, daEudemon™ AIO800 Cikakken Tsarin Gano Acid Nucleic Atomatik, hade da a14-pathogen numfashi panel, yana ba da mafita mai canzawa - isar da gaskiya"Sample in, answer out"bincike a cikin mintuna 30 kacal.
Wannan cikakken gwajin numfashi yana ganos duka ƙwayoyin cuta da ƙwayoyin cutadaga samfurin guda ɗaya, yana ba da damar masu samar da kiwon lafiya na gaba don yin ƙarfin gwiwa, lokaci, da yanke shawara na jiyya.
Mabuɗin Siffofin Tsari waɗanda ke da mahimmanci ga Abokan cinikin ku
Cikakkun Ayyukan Aiki Na atomatik
Kasa da mintuna 5 hannu-kan lokaci. Babu buƙatar ƙwararrun ma'aikatan ƙwayoyin cuta.
- Sakamako Mai Sauri
Lokacin juyawa na mintuna 30 yana goyan bayan saitunan asibiti na gaggawa.
- 14Gano Maɓalli Multiplex Pathogen
Ganewar lokaci ɗaya na:
Kwayoyin cuta:COVID-19, mura A & B, RSV, Adv, hMPV, Rhv, Parainfluenza iri I-IV, HBoV, EV, CoV
Kwayoyin cuta:MP,Cpn, SP
-Abubuwan Reagents na Lyophilized Barga a Zazzabin ɗaki (2-30°C)
Yana sauƙaƙe ajiya da sufuri, yana kawar da dogaro da sarkar sanyi.
Tsarin Kariya Mai Ƙarfi
11-Layer anti-layi matakan ciki har da UV sterilization, HEPA tacewa, da rufaffiyar-harsa aiki aiki, da dai sauransu.
Gaggawa, cikakken ganewar ƙwayoyin cuta shine ginshiƙi ga tsarin zamani na cututtukan cututtukan numfashi na yara. Tsarin AIO800, tare da cikakken sarrafa kansa, mintuna 30, kwamitin PCR mai yawa, yana ba da mafita mai amfani don saitunan layin gaba. Ta hanyar ba da damar ganowa da wuri da daidai na RSV, HMPV, da sauran mahimman ƙwayoyin cuta, yana ba wa likitoci damar yin shawarwarin jiyya da aka yi niyya, haɓaka amfani da ƙwayoyin cuta, da aiwatar da ingantaccen kulawar kamuwa da cuta-ƙarshen inganta kulawar haƙuri da ingantaccen kiwon lafiya.
#RSV #HMPV #Rapid #Ganowa #Hanyar numfashi #Pathogen #Sample-da-Amsa#MacroMicroTest
Lokacin aikawa: Dec-02-2025