Juriya na rigakafin ƙwayoyin cuta (AMR) ya zama ɗaya daga cikin manyan barazanar lafiyar jama'a na wannan ƙarni, wanda ke haifar da mutuwar sama da miliyan 1.27 a kowace shekara tare da ba da gudummawa ga ƙarin ƙarin asarar rayuka kusan miliyan 5 - wannan matsalar lafiya ta duniya cikin gaggawa tana buƙatar ɗaukar matakin gaggawa.
Wannan makon Fadakarwa na AMR na Duniya (Nuwamba 18-24), shugabannin kiwon lafiya na duniya sun haɗu a cikin kiransu:"Yi aiki Yanzu: Kare Yanzun mu, Ka Tabbatar da makomarmu."Wannan jigon yana jaddada gaggawar magance AMR, yana buƙatar ƙoƙarin haɗin gwiwa a cikin lafiyar ɗan adam, lafiyar dabbobi, da sassan muhalli.
Barazanar AMR ya zarce iyakokin ƙasa da yankunan kiwon lafiya. Dangane da binciken Lancet na baya-bayan nan, ba tare da ingantaccen shisshigi akan AMR ba,Adadin mace-macen duniya na iya kaiwa miliyan 39 nan da shekarar 2050, yayin da ake hasashen kudin da ake kashewa na shekara-shekara na maganin cututtuka masu jure wa magunguna zai karu daga dala biliyan 66 na yanzu zuwa$159 biliyan.
Rikicin AMR: Tsananin Gaskiyar Bayan Lambobi
Antimicrobial resistance (AMR) yana faruwa ne lokacin da ƙananan ƙwayoyin cuta-kwayoyin cuta, ƙwayoyin cuta, parasites, da fungi-ba su ƙara amsa magungunan rigakafi na al'ada ba. Wannan matsalar lafiya ta duniya ta kai matsayi mai ban tsoro:
-Kowane minti 5, mutum 1 ya mutu daga kamuwa da cutar rigakafi
- By2050AMR na iya rage GDP na duniya da 3.8%
-96% na kasashe(186 duka) sun shiga cikin binciken binciken AMR na duniya na 2024, yana nuna yaɗuwar wannan barazanar.
-A cikin rukunin kulawa mai zurfi a wasu yankuna.sama da kashi 50% na warewar ƙwayoyin cutanuna juriya ga aƙalla maganin rigakafi guda ɗaya
Yadda Magungunan rigakafi suka kasa: Hanyoyin Kare ƙwayoyin ƙwayoyin cuta
Magungunan rigakafi suna aiki ta hanyar niyya mahimman hanyoyin ƙwayoyin cuta:
-Tsarin bangon salula: Penicillins suna lalata bangon ƙwayoyin ƙwayoyin cuta, suna haifar da fashewar ƙwayoyin cuta da mutuwa
-Samuwar ProteinTetracyclines da macrolides suna toshe ribosomes na kwayan cuta, suna dakatar da haɗin furotin
-Kwafin DNA/RNAFluoroquinolones sun hana enzymes da ake buƙata don kwafin DNA na kwayan cuta
-Mutuncin Kwayoyin Halitta: Polymyxins suna lalata membranes na ƙwayoyin cuta, wanda ke haifar da mutuwar tantanin halitta
-Hanyoyi na MetabolicSulfonamides suna toshe mahimman hanyoyin ƙwayoyin cuta kamar haɗin folic acid
Duk da haka, ta hanyar zaɓin yanayi da maye gurbin kwayoyin halitta, ƙwayoyin cuta suna haɓaka hanyoyin da yawa don tsayayya da maganin rigakafi, ciki har da samar da enzymes marasa aiki, canza maƙasudin miyagun ƙwayoyi, rage tarin ƙwayoyi, da samar da biofilms.
Carbapenemase: "Super Makami" a cikin Rikicin AMR
Daga cikin daban-daban juriya hanyoyin, samar dacarbapenemasesyana da mahimmanci musamman. Wadannan enzymes suna hydrolyze maganin rigakafi carbapenem - yawanci ana la'akari da magungunan "layi na ƙarshe". Carbapenemases suna aiki azaman “super makamai” na kwayan cuta, suna lalata maganin rigakafi kafin su shiga ƙwayoyin ƙwayoyin cuta. Kwayoyin dauke da wadannan enzymes-kamarKlebsiella ciwon huhukumaAcinetobacter baumannii-zai iya tsira kuma ya ninka koda lokacin da aka fallasa su ga mafi yawan maganin rigakafi.
Mafi firgita, kwayoyin halittar carbapenemases suna samuwa akan abubuwan kwayoyin halitta ta hannu waɗanda zasu iya canzawa tsakanin nau'ikan ƙwayoyin cuta daban-daban,hanzarta yaduwar ƙwayoyin cuta masu jure wa magunguna da yawa a duniya.
Bincikes: Layin Farko na Tsaro a cikin AMR Control
Madaidaici, saurin bincike yana da mahimmanci wajen yaƙar AMR. Gane kan lokaci na ƙwayoyin cuta masu juriya na iya:
-Jagora madaidaicin magani, guje wa amfani da ƙwayoyin cuta marasa inganci
-A aiwatar da matakan kariya daga kamuwa da cuta don hana yaduwar ƙwayoyin cuta masu juriya
- Kula da juriya don sanar da shawarar lafiyar jama'a
Maganganun mu: Sabbin kayan aikin don Madaidaicin Yaƙin AMR
Don magance ƙalubalen AMR mai girma, Macro & Micro-Test sun haɓaka sabbin kayan gano carbapenemase guda uku waɗanda ke saduwa da buƙatun asibiti daban-daban, suna taimaka wa masu ba da lafiya da sauri da gano ƙwayoyin cuta masu juriya don tabbatar da saƙon lokaci da ingantaccen sakamakon haƙuri.
1. Kayan Gano Carbapenemase (Colloidal Zinare)
Yana amfani da fasahar gwal na colloidal don saurin gano carbapenemase abin dogaro. Ya dace da asibitoci, dakunan shan magani, har ma da amfani da gida, sauƙaƙe tsarin gano cutar tare da daidaito mai yawa.
Babban Amfani:
-Cikakken Ganewa: A lokaci guda yana gano ƙwayoyin juriya guda biyar-NDM, KPC, OXA-48, IMP, da VIM
-Sakamako cikin gaggawa: Yana ba da sakamako a cikiMinti 15, da sauri fiye da hanyoyin gargajiya (kwanaki 1-2)
-Aiki Mai Sauƙi: Babu hadaddun kayan aiki ko horo na musamman da ake buƙata, dacewa da saitunan daban-daban
-Babban Daidaito: 95% hankali ba tare da wata hujja ta ƙarya ba daga ƙwayoyin cuta na kowa kamar Klebsiella pneumoniae ko Pseudomonas aeruginosa
2. Carbapenem Resistance Gene Gane Kit (Fluorescence PCR)
An tsara shi don zurfin nazarin kwayoyin halitta na juriya na carbapenem. Manufa don cikakken sa ido a cikin dakunan gwaje-gwaje na asibiti, yana ba da ainihin gano ƙwayoyin juriya na carbapenem da yawa.
Babban Amfani:
-Samfura mai sassauƙa: Gano kai tsaye dagatsarkakakkun mazauna, sputum, ko swabs-babu al'adaake bukata
-Rage Kuɗi: Yana gano mahimman ƙwayoyin juriya guda shida (NDM, KPC, OXA-48, OXA-23) IMP, da VIM a cikin gwaji guda ɗaya, yana kawar da ƙarin gwaji.
-Babban Hankali da Takamaiman: Iyakar ganowa kamar ƙasa da 1000 CFU / mL, babu giciye-reactivity tare da sauran juriya genes kamar CTX, mecA, SME, SHV, da TEM
-Faɗin Daidaitawa: Mai jituwa daMisali-zuwa-AmsaAIO 800 cikakken POCT kwayoyin halitta mai sarrafa kansa da kayan aikin PCR na yau da kullun
3. Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa da Resistance Genes Multiplex Detection Kit (Fluorescence PCR)
Wannan kit ɗin yana haɗawa da gano ƙwayoyin cuta da hanyoyin juriya masu alaƙa cikin tsari guda ɗaya da aka daidaita don ingantaccen ganewar asali.
Babban Amfani:
-Cikakken Ganewa: lokaci guda yana ganowamanyan ƙwayoyin cuta guda uku-Klebsiella pneumoniae, Acinetobacter baumannii, da Pseudomonas aeruginosa-kuma ya gano kwayoyin halittar carbapenemase guda hudu (KPC, NDM, OXA48, da IMP) a cikin gwaji daya.
-Babban Hankali: Iya iya gano DNA na kwayan cuta a ƙananan ƙananan kamar 1000 CFU/ml
-Yana Goyan bayan Shawarar Clinical: Yana sauƙaƙa zaɓin ingantattun magungunan rigakafin ƙwayoyin cuta ta hanyar gano nau'ikan juriya da wuri
-Faɗin Daidaitawa: Mai jituwa daMisali-zuwa-AmsaAIO 800 cikakken POCT kwayoyin halitta mai sarrafa kansa da kayan aikin PCR na yau da kullun
Wadannan na'urorin ganowa suna ba da kwararrun likitocin kiwon lafiya da kayan aiki don magance AMR a matakai daban-daban-daga saurin gwajin kulawa zuwa cikakken nazarin kwayoyin halitta-tabbatar da shiga tsakani na lokaci da kuma rage yaduwar kwayoyin cuta.
Yin yaƙi da AMR tare da Madaidaicin Gano
A Macro & Micro-Test, muna samar da na'urorin bincike na yanke-yanke waɗanda ke ƙarfafa masu ba da kiwon lafiya da sauri, ingantaccen fahimta, ba da damar gyare-gyaren jiyya na lokaci da ingantaccen sarrafa kamuwa da cuta.
Kamar yadda aka jaddada yayin Makon Fadakarwa na AMR na Duniya, zaɓinmu a yau zai ƙayyade ikonmu na kare al'ummomin yanzu da na gaba daga barazanar juriyar ƙwayoyin cuta.
Haɗa yaƙi da juriya na ƙwayoyin cuta-kowace rayuwa cetar al'amura.
For more information, please contact: marketing@mmtest.com
Lokacin aikawa: Nuwamba-19-2025