Wani bincike da aka yi kwanan nan kan kwayoyin cuta ya nuna nau'ikan ƙwayoyin cuta da ƙwayoyin cuta daban-daban da beraye ke ɗauke da su a lardin Heilongjiang, ciki har da ƙwayar cutar Lassa, ƙwayar cutar Amur, Salmonella, da Yersinia pestis.
Binciken ya yi amfani da fasaharKit ɗin Inganta RNA na Pathogen daga Macro & Micro-Gwajin, bisa ga fasahar kamawa ta bincike. Ta hanyar rage rRNA mai masaukin baki da sauran gutsuttsuran mai masaukin baki da aka adana, hanyar ta riƙe RNA na ƙwayoyin cuta yadda ya kamata, wanda hakan ya inganta yanayin gano ƙwayoyin cuta sosai. Wannan matakin haɓaka RNA na ƙwayoyin cuta ya kasance mai mahimmanci wajen cimma babban ƙimar ganowa kuma ya samar da goyon baya mai ƙarfi na fasaha don sa ido kan ƙwayoyin cuta.
Beraye: Manyan Ma'ajiyar Ruwa na Cututtukan Zoonotic
Beraye su ne rukuni mafi wadata a nau'ikan dabbobi masu shayarwa kuma sun yaɗu sosai, waɗanda suka ƙunshi nau'ikan dabbobi sama da 2,000 a duk duniya kuma sun kai sama da kashi 40% na dukkan nau'ikan dabbobi masu shayarwa.
Bayan muhimmancin muhallinsu, beraye suna aiki a matsayin manyan ma'ajiyar halittu da kuma masu yada cututtuka da dama na zoonotic.Domin kuwa wuraren da beraye ke zama suna haɗuwa da muhallin ɗan adam—ta hanyar cizon kai tsaye, hulɗa da najasa, ko kuma yaɗuwar cutar ta hanyar ƙuma da ƙwari—cututtukan da suke ɗauke da su suna haifar da barazanar lafiyar jama'a.
Abin lura shi ne, sama da kashi 70% na cututtukan da ke tasowa suna fitowa ne daga namun daji, inda beraye ke wakiltar ɗaya daga cikin manyan wuraren adana ƙwayoyin cuta.
Yankin Iyakar Heilongjiang: Hanya Ta Gaba Don Kula da Cututtukan da Suka Shafi Mummunan Halittu
Heilongjiang, wani lardi da ke kan iyaka a arewa maso gabashin kasar Sin, yana da wadataccen albarkatun muhalli kuma yana da iyaka da kasashe da dama. Hadin kan halittu masu wadata da kuma yawan jama'a da ke ketare iyaka yana samar da yanayi mai kyau don yaduwar cututtuka.
Tsakanin watan Yuni da Yulin 2021, masu bincike sun tattara beraye 67 na daji daga garin Hengdaohezi, birnin Mudanjiang. Samfuran sun haɗa da:
l 20yankin Apodemus
l 47Myodes rufocanus
An kama dukkan samfuran a yankunan zama da gonaki da ke kewaye, wanda hakan ya nuna kusancin da ke tsakanin matsugunan mutane da kuma wuraren zama na namun daji.
Fasahar Inganta Cututtukan Cututtuka: Cin Nasara Kan Shisshigi A Bayan Mai Ba da Bayani
A cikin tsarin metagenomic, RNA mai masaukin baki yawanci yana mamaye karatun jerin abubuwa, yana ɓoye alamun ƙwayoyin cuta marasa yawa.
Don magance wannan ƙalubalen, an yi amfani da binciken da aka yiKit ɗin Gano Cututtukan Metagenomic na Macro & Micro-Gwajin. Ta amfani da fasahar kama na'urar bincike, na'urorin bincike da aka tsara musamman suna ɗaurewa zuwa ga rRNA mai masaukin baki da kuma jerin da aka kiyaye, wanda ke ba da damar raguwarsu da kuma wadatar da RNA na ƙwayoyin cuta.
Wannan hanyar ta inganta fahimtar gano ƙwayoyin cuta sosai, tana ba da damar yin jerin gwanon ƙwayoyin cuta don dawo da mafi yawan adadin ƙwayoyin cuta. Matakin haɓaka ƙwayoyin cuta ya kafa harsashi mai ƙarfi don tantance nau'in ƙwayoyin cuta da beraye ke ɗauke da su daidai.
Bayan an ƙara wa samfuran RNA suna, an yi musu juyin juya hali, gina ɗakin karatu, da kuma yin jerin gwanon bayanai masu inganci. Binciken bioinformatic ya haɗa da:
l Tace kwayoyin halitta mai masaukin baki
l Rarraba Taxonomic ta amfani da Kraken2
l Gyaran yalwa tare da Bracken
Wannan aikin ya haifar da cikakken bayanin al'ummomin ƙwayoyin cuta da ƙwayoyin cuta.
Binciken Bincike: Yaɗuwar ƙwayoyin cuta da ƙwayoyin cuta da yawa tare
Binciken Kwayar cuta
Kwayoyin cutar da aka gano sun fito ne daga iyalai 21 na kwayar cutar, ciki har daArenaviridaekumaHantaviridae.
Ta hanyarna sabuwar shekaraAn haɗa ta amfani da Megahit, an samar da ƙwayoyin cuta guda 154, daga cikinsu 110 sun yi daidai da ƙwayoyin cuta guda 19 daga iyalai takwas.
In yankin Apodemus, an gano ƙwayoyin cuta masu zuwa:
l Arenaviruses: cutar Lassa, cutar Wenzhou, cutar Gairo
l Hantaviruses: cutar Amur, cutar Puumala
In Myodes rufocanusAn gano cutar beraye arterivirus da kuma cutar Amur.
Daga cikin waɗannan pathogens:
Kwayar cutar Lassa cuta ce da ke haifar da zazzaɓin jini, inda adadin mace-macen da ake samu ya kai kusan kashi 20%.
Kwayar cutar Amur tana ɗaya daga cikin ƙwayoyin cuta da ke haifar da zazzaɓin jini tare da cutar koda (HFRS). China ta ba da rahoton mafi girman nauyin kamuwa da cutar hantavirus a duniya.
Binciken Kwayoyin cuta
An yi bayanin jimillar nau'ikan ƙwayoyin cuta 1,051.
Mafi yawan nau'ikan sune:
lSalmonella(26–31%)
lYersinia(11–23%)
Salmonellawata babbar cuta ce da ake kamuwa da ita ta hanyar abinci, wadda ke da alhakin kimanin mutane miliyan 9 da ke fama da zazzabin typhoid da kuma mutuwar mutane kusan 110,000 a kowace shekara a duniya.
Yersinia pestis, wanda shine sanadin annobar, ya kasance shine sanadin annoba guda uku da suka faru a tarihi. An san Lardin Heilongjiang a matsayin ɗaya daga cikin wuraren da annobar ta samo asali a China kuma har yanzu yankin da aka fi mayar da hankali a kai shine yankin da aka fi mayar da hankali a kai don sa ido kan annobar.
Muhimmancin Nazarin
Gudummawar Kimiyya
Wannan binciken ya wakilci rahoton farko na gutsuttsuran ƙwayoyin cutar Lassa da ƙwayar cutar arteritis ta bera a cikin beraye daga Heilongjiang, yana faɗaɗa bayanan ƙwayoyin cuta da beraye ke ɗauke da su a China.
Yana nuna al'ummomin ƙwayoyin cuta da ƙwayoyin cuta a cikin al'ummomin beraye na gida, yana samar da bayanai na asali don sa ido kan cututtukan zoonotic a yankunan kan iyakoki.
Tasirin Lafiyar Jama'a
Sakamakon ya nuna buƙatar ci gaba da sa ido da kuma tantance ƙwayoyin cutaA. yankin tsibiraikumaM. rufocanus.
Bayanan sun bayar da shaidar kimiyya da ke tallafawa dabarun sarrafa tushen cututtuka kamar annoba da zazzabin jini tare da cutar koda.
Ƙarfin Hanyar
Tsarin metagenomic yana ba da damar gano ƙwayoyin cuta da aka sani da kuma sabbin ƙwayoyin cuta ba tare da son zuciya ba.
A cikin wannan binciken, fasahar haɓaka ƙwayoyin cuta ta Macro & Micro-Test ta nuna ƙarfin aiki, tana inganta gano ƙwayoyin cuta masu haɗari a cikin samfuran halittu masu rikitarwa. Sakamakon ya tabbatar da ikonta na tallafawa gano ƙwayoyin cuta masu saurin kamuwa da cuta a cikin sa ido kan namun daji.
Shawarar Samfuri
Dangane da nasarar da aka samu a wannan binciken, ana ba da shawarar sosai ga Kit ɗin Inganta Kwayoyin Halittar RNA na Macro & Micro-Test don binciken sa ido kan metagenomic.
Ta hanyar rage yawan ƙwayoyin cuta masu ɗauke da ƙwayoyin cuta da kuma wadatar da jerin ƙwayoyin cuta, kayan aikin yana inganta saurin gano ƙwayoyin cuta da ingancin bayanai sosai. Yana wakiltar muhimmin kayan aiki don gano ƙwayoyin cuta daidai a cikin samfuran rikitarwa kuma yana ba da goyon bayan fasaha mai ƙarfi don sa ido kan lafiyar jama'a, kimanta haɗarin zoonotic, da shirye-shiryen barkewar cutar.
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Lokacin Saƙo: Maris-02-2026