Mycobacterium Tuberculosis INH Resistance

Takaitaccen Bayani:

Ana amfani da wannan kit ɗin don gano maye gurbi na 315th amino acid na katG gene (K315G>C) da kuma maye gurbi na yankin mai talla na kwayar InhA (- 15 C>T).


Cikakken Bayani

Tags samfurin

Sunan samfur

HWTS-RT002A-Mycobacterium tarin fuka Isoniazid Resistance Kit (Fluorescence PCR)

Takaddun shaida

Myanmar FDA

Epidemiology

Isoniazid, wani mahimmin maganin cutar tarin fuka da aka gabatar a cikin 1952, yana ɗaya daga cikin magunguna mafi inganci don haɗakar maganin tarin fuka da kuma magani guda ɗaya don cutar ta latent.

KatG shine babban kwayar halittar catalase-peroxidase da maye gurbi na katG na iya haɓaka haɗin bangon tantanin halitta na mycolic acid, yana sa ƙwayoyin cuta su jure wa isoniazid.Maganar KatG tana da alaƙa mara kyau tare da canje-canje a cikin INH-MIC, da raguwar ninki 2 a sakamakon katG a cikin ƙaramin ƙarar ninki 2 a cikin MIC.Wani dalili na juriya na isoniazid a cikin tarin fuka na mycobacterium yana faruwa lokacin shigar da tushe, gogewa ko maye gurbi ya faru a cikin kwayar halittar InhA na tarin fuka na mycobacterium.

Tashoshi

ROX inhA (-15C>T) site ·
CY5

katG (315G>C).

VIC (HEX)

IS6110

Ma'aunin Fasaha

Adana ≤-18℃ A cikin duhu
Rayuwar rayuwa

watanni 12

Nau'in Samfura

Sputum

CV ≤5.0%
LoD

1 × 103kwayoyin cuta/ml

Musamman Ba tare da giciye ba tare da maye gurbi na wuraren juriya na magunguna guda huɗu (511, 516, 526 da 531) na rpoB gene a waje da kewayon gano kayan ganowa.

Kayayyakin aiki:

Abubuwan da aka Aiwatar da Biosystems 7500 Tsarin PCR na Gaskiya

Abubuwan da aka Aiwatar da Tsarin Halittu 7500 Tsarin PCR Mai Saurin Real-Time

QuantStudio®5 Tsarin PCR na Gaskiya

SLAN-96P Tsarin PCR na Gaskiya

LightCycler®480 Tsarin PCR na Gaskiya

LineGene 9600 Plus Tsarin Gane PCR na Gaskiya

MA-6000 Mai ƙididdige yawan zafin jiki na ainihi

BioRad CFX96 Tsarin PCR na Gaskiya

BioRad CFX Opus 96 Tsarin PCR na Gaskiya

Gudun Aiki

4697e0586927f02cf6939f68fc30ffc


  • Na baya:
  • Na gaba:

  • Ku rubuta sakonku anan ku aiko mana