Enterococcus mai jure wa Vancomycin da kwayar halittar da ke jure wa magunguna

Juriya ga Magani kuma ana kiranta da juriya ga magunguna, yana nufin juriyar ƙwayoyin cuta ga aikin magungunan ƙwayoyin cuta. Da zarar juriya ga magunguna ta faru, tasirin chemotherapy na magunguna zai ragu sosai. Juriya ga Magani yana raba zuwa juriya ta ciki da juriya da aka samu. Juriya ta ciki ana ƙaddara ta hanyar kwayoyin halittar ƙwayoyin cuta na chromosomal, waɗanda aka watsa daga tsara zuwa tsara, kuma ba za su canza ba. Juriya da aka samu ta faru ne saboda gaskiyar cewa bayan hulɗa da maganin rigakafi, ƙwayoyin cuta suna canza hanyoyin rayuwa nasu don kada a kashe su ta hanyar maganin rigakafi.

Kwayoyin halittar da ke jure wa vancomycin VanA da VanB suna da juriya ga magunguna, daga cikinsu VanA yana nuna matakan juriya ga vancomycin da teicoplanin, VanB yana nuna matakai daban-daban na juriya ga vancomycin, kuma yana da saurin kamuwa da teicoplanin. Sau da yawa ana amfani da Vancomycin a asibiti don magance cututtukan ƙwayoyin cuta masu jure wa Gram-positive, amma saboda fitowar enterococci masu jure wa vancomycin (VRE), musamman enterococcus faecalis da enterococcus faecium, waɗanda suka kai sama da kashi 90%, ya kawo sabbin ƙalubale ga maganin asibiti. A halin yanzu, babu takamaiman maganin kashe ƙwayoyin cuta don maganin VRE. Bugu da ƙari, VRE kuma yana iya aika kwayoyin halittar juriya ga magunguna zuwa wasu enterococci ko wasu ƙwayoyin cuta masu jure wa Gram-positive.