Mutum TEL-AML1 Fusion Gene Mutation
Sunan samfur
HWTS-TM016 Human TEL-AML1 Fusion Gene mutation Kit (Fluorescence PCR)
Epidemiology
M cutar sankarar lymphoblastic (ALL) ita ce mafi yawan malignancy a yara. A cikin 'yan shekarun nan, m cutar sankarar bargo (AL) ya canza daga nau'in MIC (morphology, immunology, cytogenetics) zuwa nau'in MICM (ƙari na gwajin kwayoyin halitta). A cikin 1994, an gano cewa haɗin TEL a cikin ƙuruciya ya haifar da shi ta hanyar fassarar chromosomal ba da gangan ba t (12;21) (p13; q22) a cikin layin B-lineage m lymphoblastic leukemia (ALL). Tun lokacin da aka gano kwayar halittar AML1, kwayar halittar TEL-AML1 ita ce hanya mafi kyau don yin hukunci akan hasashen yara masu fama da cutar sankarar lymphoblastic.
Tashoshi
| FAM | TEL-AML1 fusion gene |
| ROX | Ikon Cikin Gida |
Ma'aunin Fasaha
| Adana | ≤-18℃ |
| Rayuwar rayuwa | watanni 9 |
| Nau'in Samfura | samfurin kasusuwa |
| Ct | ≤40 |
| CV | <5.0% |
| LoD | 1000 Kwafi/ml |
| Musamman | Babu wani giciye-reactivity tsakanin kits da sauran fusion genes kamar BCR-ABL, E2A-PBX1, MLL-AF4, AML1-ETO, PML-RARa fusion genes. |
| Abubuwan da ake Aiwatar da su | Abubuwan da aka Aiwatar da Biosystems 7500 Tsarin PCR na Gaskiya Abubuwan da aka Aiwatar da Tsarin Halittu 7500 Tsarin PCR Mai Saurin Real-Time QuantStudio®5 Tsarin PCR na Gaskiya SLAN-96P Tsarin PCR na Gaskiya LightCycler®480 Tsarin PCR na Gaskiya LineGene 9600 Plus Tsarin Gane PCR na Gaskiya MA-6000 Mai ƙididdige yawan zafin jiki na ainihi BioRad CFX96 Tsarin PCR na Gaskiya BioRad CFX Opus 96 Tsarin PCR na Gaskiya |
Gudun Aiki
RNAprep Tsabtataccen Jini Total RNA Hakar Kit (DP433).
