'Yan Adam Egfr Gemje 29

Kiwon daji na huhu ya zama babban dalilin mutuwar mutuwar cutar kansa, a duk duniya barazanar lafiyar ɗan adam. A asusunka da ba karamin labarin sel na ciwon sel na kusan kashi 80% na marasa lafiyar mahaifa ba. Egfr a halin yanzu mafi mahimmancin maƙasudi na ƙwayoyin cuta don lura da rashin karamin ciwon sel ciwon ta. Phosphration na Egfr na iya inganta ciwan jiki na tsiro, bambance-bambancen, mamaye, etastasasis, anti-apoptosis, da haɓaka ƙwayar ƙwayar cuta. Egfr Tyrosine Kinase inhibibitors (Tki) na iya toshe hanyoyin shiga Egfr ta hanyar hana haihuwa da bambancin ƙwayar cuta, da sauransu, don cimma buri na ƙwayar cuta da yawa. Babban adadin karatu ya nuna cewa ingantaccen ingancin egfr-tki yana da alaƙa da matsayin maye gurbi tare da maye gurbi na ƙwayoyin cuta tare da cutar ta Egfr. Gashin Egfr yana kan tafin tafinan chromosome 7 (7P12), tare da cikakken tsawon 200kb kuma ya ƙunshi Umarni 28. Yankin da aka maye gurbinsa shine yafi yankin da ke cikin Erons 1846 zuwa 746 zuwa ga kimanin kashi 21% na kusan 40% na kusan 40% zuwa 45%. Jagororin NCCN don ganewar asali da kuma lura da rashin karancin ciwon sel na a bayyane cewa ana buƙatar musun maye gurbi na EGFR kafin gwamnati ta maye gurbin Egfr-TKI. Ana amfani da kit ɗin gwajin don jagorantar Gudanar da Epidmal Hactor Levtror Tyrosine Kinkase inhibor (Egfr-Tki) don keɓaɓɓen magani tare da ƙananan cutar sankara. Ana amfani da wannan kit don gano abubuwan maye gurbi a cikin aikin Egfr a cikin marasa lafiya da rashin karamin cutar sankara. Sakamakon gwajin shine don tunani na asibiti kawai kuma bai kamata a yi amfani dashi azaman tushen kawai ga keɓaɓɓen magani na marasa lafiya ba. Ya kamata likitoci suyi la'akari da yanayin mai haƙuri, alamun alamun magani, da kuma kulawa da alamun binciken gwaji da sauran dalilai ana amfani dasu don yin hukunci da sakamakon gwajin.