Dan adam eml4-alk mayu

Ana amfani da wannan kit ɗin don gano nau'ikan maye gurbi 12 na Eml4-Alk Foon Get Combles na ɗan Adam Cikin ƙananan ƙwaƙwalwar ƙwayar cuta na ɗan Adam na ciwon ciki a cikin vitro. Sakamakon gwajin shine don tunani na asibiti kawai kuma bai kamata a yi amfani dashi azaman tushen kawai ga keɓaɓɓen magani na marasa lafiya ba. Calicians sun yi hukunce-hukuncen gwaji game da sakamakon gwajin dangane da dalilai na haƙuri, martanin magani, da sauran alamun gwaji. Cutar sankarar mahaifa ita ce mafi yawan cutar da cuta ta kowa a duniya, kuma 80% ~ 85% na shari'ar da ba karamin karar sel mai lashe ba (NSCLC). Gashin kansa na Echinoderm Microtubule-mai alaƙa miliyan tushe nau'i-nau'i. Akalla bambance-bambancen na fushin 20 na Fuion, waɗanda ke da maye 12 na 12 na gama gari, a cikin maye gurbi 1 (E13; A20), A20; A20 33% da 29% na marasa lafiya da eml4-alk mayon gene nsclc, bi da bi. Alkonarin da aka nuna a CrivotinB sune ƙananan kwayoyin kwayoyin da aka yi niyya don magungunan sakewa na alkama. Ta hanyar hana yawan ayyukan Alk Tyrosine na ALK, wanda ya saukar da hanyoyin sanya hannu na bakin ciki, da hakan ta hana ci gaban ƙwayoyin tumor. Karatun asibiti ya nuna cewa Crizotinib yana da yawan inganci na fiye da 61% a cikin marasa lafiya na Eml4-Alk Fusion, yayin da kusan babu tasiri a kan masu cutar daji. Sabili da haka, ganowarsa na Mataimakin Mata shine farawa da tushe don jagorantar amfani da magungunan Crizotinib.